Oral Contraceptives and Blood Coagulation

Effects of low-dose oral contraceptives on blood coagulation.

A study has been performed on the effect of Norinyl-1 and Ortho-Novin, two low-dose oral contraceptives, on blood-clotting factors. Ortho-Novin contains twice the amount of hormone as Norinyl-1. It was therefore possible to observe whether any changes detected were related to the dose of oestrogen-progestin combination. The women were tested in parallel with matched normal female controls and a...

Oral contraceptives, ABO blood types and thromboembolism.

Coagulation studies in haemophilic patients taking oral contraceptives.

Coagulation studies were performed on haemophilic patients during a controlled trial of oral contraceptive therapy. Treatment with a combined oestrogen-progestogen preparation was associated with a significant rise in the factor VII-X complex. This change was not observed during treatment with progestogen alone. The highest levels of factor IX and fibrinogen and the lowest levels of factor X we...

Oral Contraceptives

Current low dose OCs are highly effective with an excellent safety profile and many associated health benefits No single product has been shown to be superior in efficacy, safety or tolerability There is no "one size fits all" OC; different women may require different formulations Smoking particularly after age 35 with concurrent OC use greatly increases cardiovascular and thrombotic risks Age ...

Oral contraceptives and exercise.

A laboratory study was undertaken with volunteer females (aged 20-25) to determine the effect of OCs (oral contraceptives) on hematologic and metabolic variables during exercise. 5 of the women studied were naturally cycling and 7 were taking OCs. The women worked at 2 workloads on a bicycle ergometer at 50% and 90% of their maximal aerobic capacity during 3 different phases of their menstrua...